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An Individual Participant Data Population Pharmacokinetic Meta-analysis of Drug-Drug Interactions between Lumefantrine and Commonly Used Antiretroviral Treatment

Treating malaria in HIV-coinfected individuals should consider potential drug-drug interactions. Artemether-lumefantrine is the most widely recommended treatment for uncomplicated malaria globally. Lumefantrine is metabolized by CYP3A4, an enzyme that commonly used antiretrovirals often induce or in...

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Detalles Bibliográficos
Autores principales: Francis, Jose, Barnes, Karen I., Workman, Lesley, Kredo, Tamara, Vestergaard, Lasse S., Hoglund, Richard M., Byakika-Kibwika, Pauline, Lamorde, Mohammed, Walimbwa, Stephen I., Chijioke-Nwauche, Ifeyinwa, Sutherland, Colin J., Merry, Concepta, Scarsi, Kimberley K., Nyagonde, Nyagonde, Lemnge, Martha M., Khoo, Saye H., Bygbjerg, Ib C., Parikh, Sunil, Aweeka, Francesca T., Tarning, Joel, Denti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179577/
https://www.ncbi.nlm.nih.gov/pubmed/32071050
http://dx.doi.org/10.1128/AAC.02394-19