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Drug Targeting of Genomic Instability in Multiple Myeloma

Genomic instability can be observed at both chromosomal and chromatin levels. Instability at the macro level includes centrosome abnormalities (CA) resulting in numerical as well as structural chromosomal changes, whereas instability at the micro level is characterized by defects in DNA repair pathw...

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Detalles Bibliográficos
Autores principales: Beksac, Meral, Balli, Sevinc, Akcora Yildiz, Dilara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179656/
https://www.ncbi.nlm.nih.gov/pubmed/32373151
http://dx.doi.org/10.3389/fgene.2020.00228