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IRF3 and IRF8 Regulate NF-κB Signaling by Targeting MyD88 in Teleost Fish

MyD88 is a conserved intracellular adaptor, which plays an important role in the innate immune system. MyD88 transmits signals for downstream of toll-like and IL-1 receptors to activate NF-κB signaling pathway, which is tightly controlled in the immune response to maintain immune intensity and immun...

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Detalles Bibliográficos
Autores principales: Yan, Xiaolong, Zhao, Xueyan, Huo, Ruixuan, Xu, Tianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179762/
https://www.ncbi.nlm.nih.gov/pubmed/32373114
http://dx.doi.org/10.3389/fimmu.2020.00606