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IRF3 and IRF8 Regulate NF-κB Signaling by Targeting MyD88 in Teleost Fish
MyD88 is a conserved intracellular adaptor, which plays an important role in the innate immune system. MyD88 transmits signals for downstream of toll-like and IL-1 receptors to activate NF-κB signaling pathway, which is tightly controlled in the immune response to maintain immune intensity and immun...
Autores principales: | Yan, Xiaolong, Zhao, Xueyan, Huo, Ruixuan, Xu, Tianjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179762/ https://www.ncbi.nlm.nih.gov/pubmed/32373114 http://dx.doi.org/10.3389/fimmu.2020.00606 |
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