Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner

Human cytomegalovirus (HCMV) is the most frequent viral cause of congenital defects and can trigger devastating disease in immune-suppressed patients. Cytotoxic lymphocytes (CD8(+) T cells and NK cells) control HCMV infection by releasing interferon-γ and five granzymes (GrA, GrB, GrH, GrK, GrM), wh...

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Detalles Bibliográficos
Autores principales: Shan, Liling, Li, Shuang, Meeldijk, Jan, Blijenberg, Bernadet, Hendriks, Astrid, van Boxtel, Karlijn J. W. M., van den Berg, Sara P. H., Groves, Ian J., Potts, Martin, Svrlanska, Adriana, Stamminger, Thomas, Wills, Mark R., Bovenschen, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179929/
https://www.ncbi.nlm.nih.gov/pubmed/32282833
http://dx.doi.org/10.1371/journal.ppat.1008426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179929/
https://www.ncbi.nlm.nih.gov/pubmed/32282833
http://dx.doi.org/10.1371/journal.ppat.1008426

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