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TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner

The HIV-1 capsid protein makes up the core of the virion and plays a critical role in early steps of HIV replication. Due to its exposure in the cytoplasm after entry, HIV capsid is a target for host cell factors that act directly to block infection such as TRIM5α and MxB. Several host proteins also...

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Detalles Bibliográficos
Autores principales: Ohainle, Molly, Kim, Kyusik, Komurlu Keceli, Sevnur, Felton, Abby, Campbell, Ed, Luban, Jeremy, Emerman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179944/
https://www.ncbi.nlm.nih.gov/pubmed/32282853
http://dx.doi.org/10.1371/journal.ppat.1008507