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TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner
The HIV-1 capsid protein makes up the core of the virion and plays a critical role in early steps of HIV replication. Due to its exposure in the cytoplasm after entry, HIV capsid is a target for host cell factors that act directly to block infection such as TRIM5α and MxB. Several host proteins also...
Autores principales: | Ohainle, Molly, Kim, Kyusik, Komurlu Keceli, Sevnur, Felton, Abby, Campbell, Ed, Luban, Jeremy, Emerman, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7179944/ https://www.ncbi.nlm.nih.gov/pubmed/32282853 http://dx.doi.org/10.1371/journal.ppat.1008507 |
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