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A single-parasite transcriptional atlas of Toxoplasma Gondii reveals novel control of antigen expression

Toxoplasma gondii, a protozoan parasite, undergoes a complex and poorly understood developmental process that is critical for establishing a chronic infection in its intermediate hosts. Here, we applied single-cell RNA-sequencing (scRNA-seq) on >5,400 Toxoplasma in both tachyzoite and bradyzoite...

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Detalles Bibliográficos
Autores principales: Xue, Yuan, Theisen, Terence C, Rastogi, Suchita, Ferrel, Abel, Quake, Stephen R, Boothroyd, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180058/
https://www.ncbi.nlm.nih.gov/pubmed/32065584
http://dx.doi.org/10.7554/eLife.54129