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Histone Deacetylase 11 Contributes to Renal Fibrosis by Repressing KLF15 Transcription

Renal fibrosis represents a key pathophysiological process in patients with chronic kidney diseases (CKD) and is typically associated with a poor prognosis. Renal tubular epithelial cells (RTECs), in response to a host of pro-fibrogenic stimuli, can trans-differentiate into myofibroblast-like cells...

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Detalles Bibliográficos
Autores principales: Mao, Lei, Liu, Li, Zhang, Tao, Qin, Hao, Wu, Xiaoyan, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180197/
https://www.ncbi.nlm.nih.gov/pubmed/32363192
http://dx.doi.org/10.3389/fcell.2020.00235