Purine and Purine Isostere Derivatives of Ferrocene: An Evaluation of ADME, Antitumor and Electrochemical Properties

Novel purine and purine isosteres containing a ferrocene motif and 4,1-disubstituted (11a−11c, 12a−12c, 13a−13c, 14a−14c, 15a−15c, 16a, 23a−23c, 24a−24c, 25a−25c) and 1,4-disubstituted (34a−34c and 35a−35c) 1,2,3-triazole rings were synthesized. The most potent cytotoxic effect on colorectal adenoca...

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Detalles Bibliográficos
Autores principales: Rep, Valentina, Piškor, Martina, Šimek, Helena, Mišetić, Petra, Grbčić, Petra, Padovan, Jasna, Gabelica Marković, Vesna, Jadreško, Dijana, Pavelić, Krešimir, Kraljević Pavelić, Sandra, Raić-Malić, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180452/
https://www.ncbi.nlm.nih.gov/pubmed/32235404
http://dx.doi.org/10.3390/molecules25071570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180452/
https://www.ncbi.nlm.nih.gov/pubmed/32235404
http://dx.doi.org/10.3390/molecules25071570

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