Cargando…
Purine and Purine Isostere Derivatives of Ferrocene: An Evaluation of ADME, Antitumor and Electrochemical Properties
Novel purine and purine isosteres containing a ferrocene motif and 4,1-disubstituted (11a−11c, 12a−12c, 13a−13c, 14a−14c, 15a−15c, 16a, 23a−23c, 24a−24c, 25a−25c) and 1,4-disubstituted (34a−34c and 35a−35c) 1,2,3-triazole rings were synthesized. The most potent cytotoxic effect on colorectal adenoca...
Autores principales: | Rep, Valentina, Piškor, Martina, Šimek, Helena, Mišetić, Petra, Grbčić, Petra, Padovan, Jasna, Gabelica Marković, Vesna, Jadreško, Dijana, Pavelić, Krešimir, Kraljević Pavelić, Sandra, Raić-Malić, Silvana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180452/ https://www.ncbi.nlm.nih.gov/pubmed/32235404 http://dx.doi.org/10.3390/molecules25071570 |
Ejemplares similares
-
Novel Bis- and Mono-Pyrrolo[2,3-d]pyrimidine and Purine Derivatives: Synthesis, Computational Analysis and Antiproliferative Evaluation
por: Bistrović Popov, Andrea, et al.
Publicado: (2021) -
Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549
por: Bistrović, Andrea, et al.
Publicado: (2017) -
Amidine- and Amidoxime-Substituted Heterocycles: Synthesis, Antiproliferative Evaluations and DNA Binding
por: Maračić, Silvija, et al.
Publicado: (2021) -
Synthesis and Anti-Proliferative Effects of Mono- and Bis-Purinomimetics Targeting Kinases
por: Bistrović, Andrea, et al.
Publicado: (2017) -
Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles
por: Racané, Livio, et al.
Publicado: (2021)