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Lapatinib, Nilotinib and Lomitapide Inhibit Haemozoin Formation in Malaria Parasites

With the continued loss of antimalarials to resistance, drug repositioning may have a role in maximising efficiency and accelerating the discovery of new antimalarial drugs. Bayesian statistics was previously used as a tool to virtually screen USFDA approved drugs for predicted β-haematin (synthetic...

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Detalles Bibliográficos
Autores principales: de Sousa, Ana Carolina C., Maepa, Keletso, Combrinck, Jill M., Egan, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180468/
https://www.ncbi.nlm.nih.gov/pubmed/32235391
http://dx.doi.org/10.3390/molecules25071571