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Molecular mechanism of acquired drug resistance in the EGFR‐TKI resistant cell line HCC827‐TR

BACKGROUND: The first‐line standard treatment of non‐small cell lung cancer (NSCLC) with EGFR mutation is EGFR‐tyrosine kinase inhibitors (TKIs). However, most patients will develop acquired resistance after 9–13 months. This study investigated novel molecular mechanisms of acquired resistance to EG...

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Detalles Bibliográficos
Autores principales: Yu, Tao, Xia, Qian, Gong, Ting, Wang, Jing, Zhong, DianSheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180561/
https://www.ncbi.nlm.nih.gov/pubmed/32163227
http://dx.doi.org/10.1111/1759-7714.13342