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Human Serum Albumin Labelled with Sterically-Hindered Nitroxides as Potential MRI Contrast Agents

Four albumin-nitroxide conjugates were prepared and tested as metal-free organic radical contrast agents (ORCAs) for magnetic resonance imaging (MRI). Each human serum albumin (HSA) carrier bears multiple nitroxides conjugated via homocysteine thiolactones. These molecular conjugates retain importan...

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Detalles Bibliográficos
Autores principales: Dobrynin, Sergey, Kutseikin, Sergei, Morozov, Denis, Krumkacheva, Olesya, Spitsyna, Anna, Gatilov, Yurii, Silnikov, Vladimir, Angelovski, Goran, Bowman, Michael K., Kirilyuk, Igor, Chubarov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180620/
https://www.ncbi.nlm.nih.gov/pubmed/32276437
http://dx.doi.org/10.3390/molecules25071709