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Lysophosphatidic Acid Inhibits Simvastatin-Induced Myocytoxicity by Activating LPA Receptor/PKC Pathway

Statins such as simvastatin have many side effects, including muscle damage, which is known to be the most frequent undesirable side effect. Lysophosphatidic acid (LPA), a kind of biolipid, has diverse cellular activities, including cell proliferation, survival, and migration. However, whether LPA a...

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Detalles Bibliográficos
Autores principales: Won, Kyung-Jong, Goh, Yu-Jin, Hwang, Sung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180799/
https://www.ncbi.nlm.nih.gov/pubmed/32230890
http://dx.doi.org/10.3390/molecules25071529