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Biophysical Screens Identify Fragments That Bind to the Viral DNA-Binding Proteins EBNA1 and LANA

The human gamma-herpesviruses Epstein–Barr virus (EBV) (HHV-4) and Kaposi’s sarcoma-associated herpesvirus (KSHV) (HHV-8) are responsible for a number of diseases, including various types of cancer. Epstein–Barr nuclear antigen 1 (EBNA1) from EBV and latency-associated nuclear antigen (LANA) from KS...

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Detalles Bibliográficos
Autores principales: Messick, Troy E., Tolvinski, Lois, Zartler, Edward R., Moberg, Anna, Frostell, Åsa, Smith, Garry R., Reitz, Allen B., Lieberman, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180839/
https://www.ncbi.nlm.nih.gov/pubmed/32290261
http://dx.doi.org/10.3390/molecules25071760