Arylaminopropanone Derivatives as Potential Cholinesterase Inhibitors: Synthesis, Docking Study and Biological Evaluation

Neurodegenerative diseases in which the decrease of the acetylcholine is observed are growing worldwide. In the present study, a series of new arylaminopropanone derivatives with N-phenylcarbamate moiety (1–16) were prepared as potential acetylcholinesterase and butyrylcholinesterase inhibitors. In...

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Detalles Bibliográficos
Autores principales: Hudcová, Anna, Kroutil, Aleš, Kubínová, Renata, Garro, Adriana D., Gutierrez, Lucas J., Enriz, Daniel, Oravec, Michal, Csöllei, Jozef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180927/
https://www.ncbi.nlm.nih.gov/pubmed/32290227
http://dx.doi.org/10.3390/molecules25071751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180927/
https://www.ncbi.nlm.nih.gov/pubmed/32290227
http://dx.doi.org/10.3390/molecules25071751

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