New Insights into 4-Anilinoquinazolines as Inhibitors of Cardiac Troponin I–Interacting Kinase (TNNi3K)

We report the synthesis of several related 4-anilinoquinazolines as inhibitors of cardiac troponin I–interacting kinase (TNNi3K). These close structural analogs of 3-((6,7-dimethoxyquinazolin-4-yl)amino)-4-(dimethylamino)-N-methylbenzenesulfonamide (GSK114) provide new understanding of structure–act...

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Detalles Bibliográficos
Autores principales: Asquith, Christopher R. M., Laitinen, Tuomo, Wells, Carrow I., Tizzard, Graham J., Zuercher, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180948/
https://www.ncbi.nlm.nih.gov/pubmed/32272798
http://dx.doi.org/10.3390/molecules25071697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180948/
https://www.ncbi.nlm.nih.gov/pubmed/32272798
http://dx.doi.org/10.3390/molecules25071697

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