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Characterization of (18)F-PM-PBB3 ((18)F-APN-1607) Uptake in the rTg4510 Mouse Model of Tauopathy

Misfolding, aggregation, and cerebral accumulation of tau deposits are hallmark features of Alzheimer’s disease. Positron emission tomography study of tau can facilitate the development of anti-tau treatment. Here, we investigated a novel tau tracer (18)F-PM-PBB3 ((18)F-APN-1607) in a mouse model of...

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Detalles Bibliográficos
Autores principales: Weng, Chi-Chang, Hsiao, Ing-Tsung, Yang, Qing-Fang, Yao, Cheng-Hsiang, Tai, Chin-Yin, Wu, Meng-Fang, Yen, Tzu-Chen, Jang, Ming-Kuei, Lin, Kun-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181044/
https://www.ncbi.nlm.nih.gov/pubmed/32290239
http://dx.doi.org/10.3390/molecules25071750