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Organosilicon Compounds, SILA-409 and SILA-421, as Doxorubicin Resistance-Reversing Agents in Human Colon Cancer Cells

Multidrug resistance (MDR) that occurs in cancer cells constitutes one of the major reasons for chemotherapy failure. The main molecular mechanism of MDR is overexpression of protein transporters from the ATP-binding cassette (ABC) superfamily, such as ABCB1 (multidrug resistance protein 1 (MDR1), P...

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Detalles Bibliográficos
Autores principales: Wesołowska, Olga, Michalak, Krystyna, Błaszczyk, Maria, Molnár, Joseph, Środa-Pomianek, Kamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181076/
https://www.ncbi.nlm.nih.gov/pubmed/32260260
http://dx.doi.org/10.3390/molecules25071654