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Sensitive Detection of Nucleic Acids Using Subzyme Feedback Cascades

The development of Subzymes demonstrates how the catalytic activity of DNAzymes can be controlled for detecting nucleic acids; however, Subzymes alone lack the sensitivity required to detect low target concentrations. To improve sensitivity, we developed a feedback system using a pair of cross-catal...

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Detalles Bibliográficos
Autores principales: Hasick, Nicole, Lawrence, Andrea, Ramadas, Radhika, Todd, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181152/
https://www.ncbi.nlm.nih.gov/pubmed/32290237
http://dx.doi.org/10.3390/molecules25071755