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A Tryptophan Metabolite, 8-Hydroxyquinaldic Acid, Exerts Antiproliferative and Anti-Migratory Effects on Colorectal Cancer Cells

8-Hydroxyquinaldic acid, the end-metabolite of tryptophan, is well-known metal chelator; however, its role in humans, especially in cancer promotion and progression, has not been fully revealed. Importantly, 8-hydroxyquinaldic acid is the analog of kynurenic acid with evidenced antiproliferative act...

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Detalles Bibliográficos
Autores principales: Walczak, Katarzyna, Langner, Ewa, Szalast, Karolina, Makuch-Kocka, Anna, Pożarowski, Piotr, Plech, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181169/
https://www.ncbi.nlm.nih.gov/pubmed/32260268
http://dx.doi.org/10.3390/molecules25071655