Theoretical Studies Aimed at Finding FLT3 Inhibitors and a Promising Compound and Molecular Pattern with Dual Aurora B/FLT3 Activity

FLT3 and dual Aurora B/FLT3 inhibitors have shown relevance in the search for promising new anticancer compounds, mainly for acute myeloid leukemia (AML). This study was designed to investigate the interactions between human FLT3 in the kinase domain with several indolin−2-one derivatives, structura...

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Detalles Bibliográficos
Autores principales: Fernandes, Ítalo Antônio, Braga Resende, Déborah, Ramalho, Teodorico Castro, Kuca, Kamil, da Cunha, Elaine Fontes Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181172/
https://www.ncbi.nlm.nih.gov/pubmed/32283751
http://dx.doi.org/10.3390/molecules25071726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181172/
https://www.ncbi.nlm.nih.gov/pubmed/32283751
http://dx.doi.org/10.3390/molecules25071726

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