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The Histone Deacetylase Inhibitor Romidepsin Spares Normal Tissues While Acting as an Effective Radiosensitizer in Bladder Tumors in Vivo

PURPOSE: Muscle-invasive bladder cancer has a 40% to 60% 5-year survival rate with radical treatment by surgical removal of the bladder or radiation therapy–based bladder preservation techniques, including concurrent chemoradiation. Elderly patients cannot tolerate current chemoradiation therapy reg...

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Detalles Bibliográficos
Autores principales: Paillas, Salome, Then, Chee K., Kilgas, Susan, Ruan, Jia-Ling, Thompson, James, Elliott, Amy, Smart, Sean, Kiltie, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier, Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181176/
https://www.ncbi.nlm.nih.gov/pubmed/31987970
http://dx.doi.org/10.1016/j.ijrobp.2020.01.015