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Codon Usage and Splicing Jointly Influence mRNA Localization
In the human genome, most genes undergo splicing, and patterns of codon usage are splicing dependent: guanine and cytosine (GC) content is the highest within single-exon genes and within first exons of multi-exon genes. However, the effects of codon usage on gene expression are typically characteriz...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181179/ https://www.ncbi.nlm.nih.gov/pubmed/32275854 http://dx.doi.org/10.1016/j.cels.2020.03.001 |