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Codon Usage and Splicing Jointly Influence mRNA Localization

In the human genome, most genes undergo splicing, and patterns of codon usage are splicing dependent: guanine and cytosine (GC) content is the highest within single-exon genes and within first exons of multi-exon genes. However, the effects of codon usage on gene expression are typically characteriz...

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Detalles Bibliográficos
Autores principales:	Mordstein, Christine, Savisaar, Rosina, Young, Robert S., Bazile, Jeanne, Talmane, Lana, Luft, Juliet, Liss, Michael, Taylor, Martin S., Hurst, Laurence D., Kudla, Grzegorz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181179/ https://www.ncbi.nlm.nih.gov/pubmed/32275854 http://dx.doi.org/10.1016/j.cels.2020.03.001

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