A Unique Gene-Silencing Approach, Using an Intelligent RNA Expression Device (iRed), Results in Minimal Immune Stimulation When Given by Local Intrapleural Injection in Malignant Pleural Mesothelioma

Background: We have recently introduced an intelligent RNA expression device (iRed), comprising the minimum essential components needed to transcribe short hairpin RNA (shRNA) in cells. Use of iRed efficiently produced shRNA molecules after transfection into cells and alleviated the innate immune st...

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Detalles Bibliográficos
Autores principales: Ando, Hidenori, Saito-Tarashima, Noriko, Lila, Amr S. Abu, Kinjo, Nozomi, Shimizu, Taro, Ishima, Yu, Minakawa, Noriaki, Ishida, Tatsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181240/
https://www.ncbi.nlm.nih.gov/pubmed/32283709
http://dx.doi.org/10.3390/molecules25071725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181240/
https://www.ncbi.nlm.nih.gov/pubmed/32283709
http://dx.doi.org/10.3390/molecules25071725

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