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A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3′UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells

Peptide nucleic acids (PNAs) have been demonstrated to be very useful tools for gene regulation at different levels and with different mechanisms of action. In the last few years the use of PNAs for targeting microRNAs (anti-miRNA PNAs) has provided impressive advancements. In particular, targeting...

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Detalles Bibliográficos
Autores principales: Sultan, Shaiq, Rozzi, Andrea, Gasparello, Jessica, Manicardi, Alex, Corradini, Roberto, Papi, Chiara, Finotti, Alessia, Lampronti, Ilaria, Reali, Eva, Cabrini, Giulio, Gambari, Roberto, Borgatti, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181265/
https://www.ncbi.nlm.nih.gov/pubmed/32260566
http://dx.doi.org/10.3390/molecules25071677