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Novel Polycondensed Partly Saturated β-Carbolines Including Ferrocene Derivatives: Synthesis, DFT-Supported Structural Analysis, Mechanism of Some Diastereoselective Transformations and a Preliminary Study of their In Vitro Antiproliferative Effects

Use of a Pictet-Spengler reaction of tryptamine and l-tryptophan methyl ester and subsequent reduction of the nitro group followed by further cyclocondensation with aryl aldehydes and formyl–substituted carboxylic acids, including ferrocene-based components, furnished a series of diastereomeric 6-ar...

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Detalles Bibliográficos
Autores principales: Fodor, Kinga Judit, Hutai, Dániel, Jernei, Tamás, Takács, Angéla, Szász, Zsófia, Sulyok-Eiler, Máté, Harmat, Veronika, Oláh Szabó, Rita, Schlosser, Gitta, Hudecz, Ferenc, Kőhidai, László, Csámpai, Antal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181298/
https://www.ncbi.nlm.nih.gov/pubmed/32244444
http://dx.doi.org/10.3390/molecules25071599