Cargando…

Novel Polycondensed Partly Saturated β-Carbolines Including Ferrocene Derivatives: Synthesis, DFT-Supported Structural Analysis, Mechanism of Some Diastereoselective Transformations and a Preliminary Study of their In Vitro Antiproliferative Effects

Use of a Pictet-Spengler reaction of tryptamine and l-tryptophan methyl ester and subsequent reduction of the nitro group followed by further cyclocondensation with aryl aldehydes and formyl–substituted carboxylic acids, including ferrocene-based components, furnished a series of diastereomeric 6-ar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fodor, Kinga Judit, Hutai, Dániel, Jernei, Tamás, Takács, Angéla, Szász, Zsófia, Sulyok-Eiler, Máté, Harmat, Veronika, Oláh Szabó, Rita, Schlosser, Gitta, Hudecz, Ferenc, Kőhidai, László, Csámpai, Antal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181298/ https://www.ncbi.nlm.nih.gov/pubmed/32244444 http://dx.doi.org/10.3390/molecules25071599

Ejemplares similares

Investigation of the Antitumor Effects of Tamoxifen and Its Ferrocene-Linked Derivatives on Pancreatic and Breast Cancer Cell Lines
por: Kalabay, Márton, et al.
Publicado: (2022)

Ferrocene-Containing Impiridone (ONC201) Hybrids: Synthesis, DFT Modelling, In Vitro Evaluation, and Structure–Activity Relationships
por: Bárány, Péter, et al.
Publicado: (2018)

Synthesis, Structure and In Vitro Cytotoxic Activity of Novel Cinchona—Chalcone Hybrids with 1,4-Disubstituted- and 1,5-Disubstituted 1,2,3-Triazole Linkers
por: Jernei, Tamás, et al.
Publicado: (2019)

The Synergistic Activity of Bortezomib and TIC10 against A2058 Melanoma Cells
por: Takács, Angéla, et al.
Publicado: (2021)

Synthesis, structure and in vitro antiproliferative effects of alkyne-linked 1,2,4-thiadiazole hybrids including erlotinib- and ferrocene-containing derivatives
por: Boulhaoua, Mohammed, et al.
Publicado: (2021)

Synthesis and SAR Analysis of Novel 4-Hydroxytamoxifen Analogues Based on Their Cytotoxic Activity and Electron-Donor Character
por: Duró, Cintia, et al.
Publicado: (2022)

Synthesis and Antiproliferative Activity of Novel Imipridone–Ferrocene Hybrids with Triazole and Alkyne Linkers
por: Czuczi, Tamás, et al.
Publicado: (2022)

Diastereoselective approach to rationally design tetrahydro-β-carboline–isatin conjugates as potential SERMs against breast cancer
por: Sharma, Bharvi, et al.
Publicado: (2019)

Acylated mono-, bis- and tris- Cinchona-Based Amines Containing Ferrocene or Organic Residues: Synthesis, Structure and in Vitro Antitumor Activity on Selected Human Cancer Cell Lines
por: Károlyi, Benedek Imre, et al.
Publicado: (2012)

Synthesis and Characterization of a Self-Polycondensation Diazaphthalanone Monomer and Its Polymers from Polycondensation Reactions
por: Liu, Xin, et al.
Publicado: (2022)

Optimisation of Glycerol and Itaconic Anhydride Polycondensation
por: Kolankowski, Krzysztof, et al.
Publicado: (2022)

The effects of mouthwashes in human gingiva epithelial progenitor (HGEPp) cells
por: Kőhidai, Zsófia, et al.
Publicado: (2022)

Polycondensation Resins by Flavonoid Tannins Reaction with Amines
por: Santiago-Medina, Francisco-Jose, et al.
Publicado: (2017)

A carbapenem antibiotic inhibiting a mammalian serine protease: structure of the acylaminoacyl peptidase–meropenem complex
por: Kiss-Szemán, Anna J., et al.
Publicado: (2022)

On the Effect of Microwave Energy on Lipase-Catalyzed Polycondensation Reactions
por: Pellis, Alessandro, et al.
Publicado: (2016)

Ultramicroporous Polyphenylenes via Diels–Alder Polycondensation Approach
por: Sorokina, Svetlana A., et al.
Publicado: (2023)

2,3-Dihydroferroceno[3,4]pyrrolo[2,1-b]thiazol-5(8b)-ones: Synthesis, Structure and DFT Study on the Mechanism of Chemo- and Diastereoslective Annulations of (S(p))-2-Formylferrocenecarbonyl Fluoride and (S(p))-2-Formylferrocenecarboxylic Acid
por: Kovács, Zoltán, et al.
Publicado: (2021)

Synthesis and characterization of new fluorescent boro-β-carboline dyes
por: Szepesi Kovács, Dénes, et al.
Publicado: (2021)

The role of halogens in the catalyst transfer polycondensation for π-conjugated polymers
por: Ye, Shuyang, et al.
Publicado: (2018)

Homoconjugated Acids as Low Cyclosiloxane-Producing Silanol Polycondensation Catalysts
por: Roberts, John M., et al.
Publicado: (2020)

Redox-Responsive Polycondensate Neoepitope for Enhanced Personalized Cancer Vaccine
por: Wei, Lixia, et al.
Publicado: (2020)

Back-to-monomer recycling of polycondensation polymers: opportunities for chemicals and enzymes
por: Thiyagarajan, Shanmugam, et al.
Publicado: (2022)

Phage Display-Based Homing Peptide-Daunomycin Conjugates for Selective Drug Targeting to PANC-1 Pancreatic Cancer
por: Dókus, Levente E., et al.
Publicado: (2020)

Phosphaalkenylidene bridged ferrocenes
por: Orthaber, Andreas, et al.
Publicado: (2012)

Highly Diastereoselective Synthesis of Spiropyrazolones
por: Ceban, Victor, et al.
Publicado: (2015)

Protoflavone-Chalcone Hybrids Exhibit Enhanced Antitumor Action through Modulating Redox Balance, Depolarizing the Mitochondrial Membrane, and Inhibiting ATR-Dependent Signaling
por: Latif, Ahmed Dhahir, et al.
Publicado: (2020)

β-Carbolines in Experiments on Laboratory Animals
por: Zawirska-Wojtasiak, Renata, et al.
Publicado: (2020)

Covalent Triazine Frameworks via a Low‐Temperature Polycondensation Approach
por: Wang, Kewei, et al.
Publicado: (2017)

Suzuki–Miyaura Catalyst-Transfer Polycondensation of Triolborate-Type Carbazole Monomers
por: Kobayashi, Saburo, et al.
Publicado: (2021)

Anionic polycondensation and equilibrium driven monomer formation of cyclic aliphatic carbonates
por: Hua, Geng, et al.
Publicado: (2018)

Thermoresponsive Polyphosphoester via Polycondensation Reactions: Synthesis, Characterization, and Self-Assembly
por: Yamakita, Yoshihiro, et al.
Publicado: (2022)

Facile, Regio- and Diastereoselective Synthesis of Spiro-Pyrrolidine and Pyrrolizine Derivatives and Evaluation of Their Antiproliferative Activities
por: Almansour, Abdulrahman I., et al.
Publicado: (2014)

Diastereoselectivity in the Staudinger reaction of pentafluorosulfanylaldimines and ketimines
por: Penger, Alexander, et al.
Publicado: (2013)

Chemo- and Diastereoselectivities in the Electrochemical Reduction of Maleimides
por: Rix, Kathryn, et al.
Publicado: (2015)

Diastereoselective Synthesis of (±)-epi-Subincanadine C
por: Kalshetti, Manojkumar G., et al.
Publicado: (2018)

Zirconocene catalyzed diastereoselective carbometalation of cyclobutenes
por: Roy, Sudipta Raha, et al.
Publicado: (2017)

Regio- and Diastereoselective Carbometalation Reaction of Cyclopropenes
por: Cohen, Yair, et al.
Publicado: (2022)

1-(Bromomercurio)ferrocene
por: Breunig, Jens M., et al.
Publicado: (2013)

Antioxidant Activity and α-Glucosidase Inhibitory Activities of the Polycondensate of Catechin with Glyoxylic Acid
por: Geng, Sheng, et al.
Publicado: (2016)

Cross-coupling polycondensation via C–O or C–N bond cleavage
por: Yang, Ze-Kun, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_drp7j3ifl62v5unfd8qpt7n0mn