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Live-Cell Imaging and Quantification of PolyQ Aggregates by Stimulated Raman Scattering of Selective Deuterium Labeling

[Image: see text] Polyglutamine (polyQ) diseases are a group of neurodegenerative disorders, involving the deposition of aggregation-prone proteins with long polyQ expansions. However, the cytotoxic roles of these aggregates remain highly controversial, largely due to a lack of proper tools for quan...

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Detalles Bibliográficos
Autores principales: Miao, Kun, Wei, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181319/
https://www.ncbi.nlm.nih.gov/pubmed/32341997
http://dx.doi.org/10.1021/acscentsci.9b01196