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Human Immune Responses to Adeno-Associated Virus (AAV) Vectors

Recombinant adeno-associated virus (rAAV) vectors are one of the most promising in vivo gene delivery tools. Several features make rAAV vectors an ideal platform for gene transfer. However, the high homology with the parental wild-type virus, which often infects humans, poses limitations in terms of...

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Detalles Bibliográficos
Autores principales: Ronzitti, Giuseppe, Gross, David-Alexandre, Mingozzi, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181373/
https://www.ncbi.nlm.nih.gov/pubmed/32362898
http://dx.doi.org/10.3389/fimmu.2020.00670