Cargando…
Human Immune Responses to Adeno-Associated Virus (AAV) Vectors
Recombinant adeno-associated virus (rAAV) vectors are one of the most promising in vivo gene delivery tools. Several features make rAAV vectors an ideal platform for gene transfer. However, the high homology with the parental wild-type virus, which often infects humans, poses limitations in terms of...
Autores principales: | Ronzitti, Giuseppe, Gross, David-Alexandre, Mingozzi, Federico |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181373/ https://www.ncbi.nlm.nih.gov/pubmed/32362898 http://dx.doi.org/10.3389/fimmu.2020.00670 |
Ejemplares similares
-
Pre-existing humoral immunity and complement pathway contribute to immunogenicity of adeno-associated virus (AAV) vector in human blood
por: Smith, Corinne J., et al.
Publicado: (2022) -
Pre-Clinical Assessment of Immune Responses to Adeno-Associated Virus (AAV) Vectors
por: Basner-Tschakarjan, Etiena, et al.
Publicado: (2014) -
Adeno-Associated Viral Vectors at the Frontier between Tolerance and Immunity
por: Mingozzi, Federico, et al.
Publicado: (2015) -
Overcoming the Challenges Imposed by Humoral Immunity to AAV Vectors to Achieve Safe and Efficient Gene Transfer in Seropositive Patients
por: Gross, David-Alexandre, et al.
Publicado: (2022) -
Cell-Mediated Immunity to AAV Vectors, Evolving Concepts and Potential Solutions
por: Basner-Tschakarjan, Etiena, et al.
Publicado: (2014)