Pre-existing neutralizing antibodies prevent CD8 T cell-mediated immunopathology following respiratory syncytial virus infection

Despite being a leading cause of severe respiratory disease, there remains no licensed respiratory syncytial virus (RSV) vaccine. Neutralizing antibodies reduce the severity of RSV-associated disease, but are not sufficient for preventing reinfection. In contrast, the role of memory CD8 T cells in p...

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Detalles Bibliográficos
Autores principales: Schmidt, Megan E., Meyerholz, David K., Varga, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181396/
https://www.ncbi.nlm.nih.gov/pubmed/31844172
http://dx.doi.org/10.1038/s41385-019-0243-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181396/
https://www.ncbi.nlm.nih.gov/pubmed/31844172
http://dx.doi.org/10.1038/s41385-019-0243-4

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