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Inhibition of formyl peptide receptors improves the outcome in a mouse model of Alzheimer disease
BACKGROUND: An important hallmark of Alzheimer’s disease (AD) is the increase of Aβ1-42 burden and its accumulation to senile plaques, leading the reactive gliosis and neurodegeneration. The modulation of glia cell function represents an attractive therapeutic strategy, but is currently limited by a...
Autores principales: | Schröder, Nicole, Schaffrath, Anja, Welter, Josua A., Putzka, Tim, Griep, Angelika, Ziegler, Patrick, Brandt, Elisa, Samer, Sebastian, Heneka, Michael T., Kaddatz, Hannes, Zhan, Jiangshan, Kipp, Eugenia, Pufe, Thomas, Tauber, Simone C., Kipp, Markus, Brandenburg, Lars-Ove |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181500/ https://www.ncbi.nlm.nih.gov/pubmed/32331524 http://dx.doi.org/10.1186/s12974-020-01816-2 |
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