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Improvement of sabinene tolerance of Escherichia coli using adaptive laboratory evolution and omics technologies
BACKGROUND: Biosynthesis of sabinene, a bicyclic monoterpene, has been accomplished in engineered microorganisms by introducing heterologous pathways and using renewable sugar as a carbon source. However, the efficiency and titers of this method are limited by the low host tolerance to sabinene (in...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181518/ https://www.ncbi.nlm.nih.gov/pubmed/32346395 http://dx.doi.org/10.1186/s13068-020-01715-x |