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Identification of early pericyte loss and vascular amyloidosis in Alzheimer’s disease retina

Pericyte loss and deficient vascular platelet-derived growth factor receptor-β (PDGFRβ) signaling are prominent features of the blood–brain barrier breakdown described in Alzheimer’s disease (AD) that can predict cognitive decline yet have never been studied in the retina. Recent reports using nonin...

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Detalles Bibliográficos
Autores principales: Shi, Haoshen, Koronyo, Yosef, Rentsendorj, Altan, Regis, Giovanna C., Sheyn, Julia, Fuchs, Dieu-Trang, Kramerov, Andrei A., Ljubimov, Alexander V., Dumitrascu, Oana M., Rodriguez, Anthony R., Barron, Ernesto, Hinton, David R., Black, Keith L., Miller, Carol A., Mirzaei, Nazanin, Koronyo-Hamaoui, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181564/
https://www.ncbi.nlm.nih.gov/pubmed/32043162
http://dx.doi.org/10.1007/s00401-020-02134-w