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Stress gates an astrocytic energy reservoir to impair synaptic plasticity

Astrocytes support the energy demands of synaptic transmission and plasticity. Enduring changes in synaptic efficacy are highly sensitive to stress, yet whether changes to astrocyte bioenergetic control of synapses contributes to stress-impaired plasticity is unclear. Here we show in mice that stres...

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Detalles Bibliográficos
Autores principales: Murphy-Royal, Ciaran, Johnston, April D., Boyce, Andrew K. J., Diaz-Castro, Blanca, Institoris, Adam, Peringod, Govind, Zhang, Oliver, Stout, Randy F., Spray, David C., Thompson, Roger J., Khakh, Baljit S., Bains, Jaideep S., Gordon, Grant R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181611/
https://www.ncbi.nlm.nih.gov/pubmed/32332733
http://dx.doi.org/10.1038/s41467-020-15778-9