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Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts
The mechanisms that underpin how insertions or deletions (indels) become fixed in DNA have primarily been ascribed to replication-related and/or double-strand break (DSB)-related processes. Here, we introduce a method to evaluate indels, orientating them relative to gene transcription. In so doing,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181645/ https://www.ncbi.nlm.nih.gov/pubmed/32332764 http://dx.doi.org/10.1038/s41467-020-15901-w |