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BCL9/STAT3 regulation of transcriptional enhancer networks promote DCIS progression

The molecular processes by which some human ductal carcinoma in situ (DCIS) lesions advance to the more aggressive form, while others remain indolent, are largely unknown. Experiments utilizing a patient-derived (PDX) DCIS Mouse INtraDuctal (MIND) animal model combined with ChIP-exo and RNA sequenci...

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Detalles Bibliográficos
Autores principales: Elsarraj, Hanan S., Hong, Yan, Limback, Darlene, Zhao, Ruonan, Berger, Jenna, Bishop, Stephanie C., Sabbagh, Aria, Oppenheimer, Linzi, Harper, Haleigh E., Tsimelzon, Anna, Huang, Shixia, Hilsenbeck, Susan G., Edwards, Dean P., Fontes, Joseph, Fan, Fang, Madan, Rashna, Fangman, Ben, Ellis, Ashley, Tawfik, Ossama, Persons, Diane L., Fields, Timothy, Godwin, Andrew K., Hagan, Christy R., Swenson-Fields, Katherine, Coarfa, Cristian, Thompson, Jeffrey, Behbod, Fariba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181646/
https://www.ncbi.nlm.nih.gov/pubmed/32352029
http://dx.doi.org/10.1038/s41523-020-0157-z