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BCL9/STAT3 regulation of transcriptional enhancer networks promote DCIS progression
The molecular processes by which some human ductal carcinoma in situ (DCIS) lesions advance to the more aggressive form, while others remain indolent, are largely unknown. Experiments utilizing a patient-derived (PDX) DCIS Mouse INtraDuctal (MIND) animal model combined with ChIP-exo and RNA sequenci...
Autores principales: | Elsarraj, Hanan S., Hong, Yan, Limback, Darlene, Zhao, Ruonan, Berger, Jenna, Bishop, Stephanie C., Sabbagh, Aria, Oppenheimer, Linzi, Harper, Haleigh E., Tsimelzon, Anna, Huang, Shixia, Hilsenbeck, Susan G., Edwards, Dean P., Fontes, Joseph, Fan, Fang, Madan, Rashna, Fangman, Ben, Ellis, Ashley, Tawfik, Ossama, Persons, Diane L., Fields, Timothy, Godwin, Andrew K., Hagan, Christy R., Swenson-Fields, Katherine, Coarfa, Cristian, Thompson, Jeffrey, Behbod, Fariba |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181646/ https://www.ncbi.nlm.nih.gov/pubmed/32352029 http://dx.doi.org/10.1038/s41523-020-0157-z |
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