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LncRNA KCNQ1OT1 sponges miR-34c-5p to promote osteosarcoma growth via ALDOA enhanced aerobic glycolysis

Metabolic switch from oxidative phosphorylation to aerobic glycolysis, which is also called the Warburg effect, is a hallmark of osteosarcoma (OS) and leads to the enhancement of cell chemoresistance, growth, metastasis, and invasion. Emerging evidence indicates that long non-coding RNA (lncRNA) pla...

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Detalles Bibliográficos
Autores principales: Shen, Yifei, Xu, Jingwen, Pan, Xiaohui, Zhang, Yunkun, Weng, Yiping, Zhou, Dong, He, Shisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181648/
https://www.ncbi.nlm.nih.gov/pubmed/32332718
http://dx.doi.org/10.1038/s41419-020-2485-1