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Elevated O-GlcNAcylation induces an antidepressant-like phenotype and decreased inhibitory transmission in medial prefrontal cortex
Depression is a devastating mental disorder affected by multiple factors that can have genetic, environmental, or metabolic causes. Although previous studies have reported an association of dysregulated glucose metabolism with depression, its underlying mechanism remains elusive at the molecular lev...
Autores principales: | Cho, Yoonjeong, Hwang, Hongik, Rahman, Md. Ataur, Chung, ChiHye, Rhim, Hyewhon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181662/ https://www.ncbi.nlm.nih.gov/pubmed/32332789 http://dx.doi.org/10.1038/s41598-020-63819-6 |
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