The IAP Antagonist SM-164 Eliminates Triple-Negative Breast Cancer Metastasis to Bone and Lung in Mice

The most challenging issue for breast cancer (BC) patients is metastasis to other organs because current therapies do not prevent or eliminate metastatic BC. Here, we show that SM-164, a small molecule inhibitor, which degrades inhibitor of apoptosis proteins (IAPs), eliminated early-stage metastase...

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Detalles Bibliográficos
Autores principales: Lei, Wei, Duan, Rong, Li, Jinbo, Liu, Xin, Huston, Alissa, Boyce, Brendan F., Yao, Zhenqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181667/
https://www.ncbi.nlm.nih.gov/pubmed/32332865
http://dx.doi.org/10.1038/s41598-020-64018-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181667/
https://www.ncbi.nlm.nih.gov/pubmed/32332865
http://dx.doi.org/10.1038/s41598-020-64018-z

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