Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages

DNA damage regulated autophagy modulator 1 (DRAM1) is a stress-inducible regulator of autophagy and cell death. DRAM1 has been implicated in cancer, myocardial infarction, and infectious diseases, but the molecular and cellular functions of this transmembrane protein remain poorly understood. Previo...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Varela, Monica, Forn-Cuní, Gabriel, Torraca, Vincenzo, van der Vaart, Michiel, Meijer, Annemarie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181687/
https://www.ncbi.nlm.nih.gov/pubmed/32332700
http://dx.doi.org/10.1038/s41419-020-2477-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181687/
https://www.ncbi.nlm.nih.gov/pubmed/32332700
http://dx.doi.org/10.1038/s41419-020-2477-1

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