The molecular chaperone Hsp90α deficiency causes retinal degeneration by disrupting Golgi organization and vesicle transportation in photoreceptors

Heat shock protein 90 (Hsp90) is an abundant molecular chaperone with two isoforms, Hsp90α and Hsp90β. Hsp90β deficiency causes embryonic lethality, whereas Hsp90α deficiency causes few abnormities except male sterility. In this paper, we reported that Hsp90α was exclusively expressed in the retina,...

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Detalles Bibliográficos
Autores principales: Wu, Yuan, Zheng, Xiudan, Ding, Yubo, Zhou, Min, Wei, Zhuang, Liu, Tao, Liao, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181719/
https://www.ncbi.nlm.nih.gov/pubmed/31408169
http://dx.doi.org/10.1093/jmcb/mjz048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181719/
https://www.ncbi.nlm.nih.gov/pubmed/31408169
http://dx.doi.org/10.1093/jmcb/mjz048

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