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Tumor cells educate mesenchymal stromal cells to release chemoprotective and immunomodulatory factors

Factors released by surrounding cells such as cancer-associated mesenchymal stromal cells (CA-MSCs) are involved in tumor progression and chemoresistance. In this study, we characterize the mechanisms by which naïve mesenchymal stromal cells (MSCs) can acquire a CA-MSCs phenotype. Ovarian tumor cell...

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Detalles Bibliográficos
Autores principales: Le Naour, Augustin, Prat, Mélissa, Thibault, Benoît, Mével, Renaud, Lemaitre, Léa, Leray, Hélène, Joubert, Marie-Véronique, Coulson, Kimberley, Golzio, Muriel, Lefevre, Lise, Mery, Eliane, Martinez, Alejandra, Ferron, Gwénaël, Delord, Jean-Pierre, Coste, Agnès, Couderc, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181721/
https://www.ncbi.nlm.nih.gov/pubmed/31504643
http://dx.doi.org/10.1093/jmcb/mjz090