Cargando…

TRIM65 E3 ligase targets VCAM-1 degradation to limit LPS-induced lung inflammation

Although the adhesion molecules-mediated leukocyte adherence and infiltration into tissues is an important step of inflammation, the post-translational regulation of these proteins on the endothelial cells is poorly understood. Here, we report that TRIM65, an ubiquitin E3 ligase of tripartite protei...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yong, Huang, Xuan, Guo, Fang, Lei, Tianhua, Li, Shitao, Monaghan-Nichols, Paula, Jiang, Zhisheng, Xin, Hong-Bo, Fu, Mingui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181722/
https://www.ncbi.nlm.nih.gov/pubmed/31310649
http://dx.doi.org/10.1093/jmcb/mjz077