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TRIM65 E3 ligase targets VCAM-1 degradation to limit LPS-induced lung inflammation
Although the adhesion molecules-mediated leukocyte adherence and infiltration into tissues is an important step of inflammation, the post-translational regulation of these proteins on the endothelial cells is poorly understood. Here, we report that TRIM65, an ubiquitin E3 ligase of tripartite protei...
Autores principales: | Li, Yong, Huang, Xuan, Guo, Fang, Lei, Tianhua, Li, Shitao, Monaghan-Nichols, Paula, Jiang, Zhisheng, Xin, Hong-Bo, Fu, Mingui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181722/ https://www.ncbi.nlm.nih.gov/pubmed/31310649 http://dx.doi.org/10.1093/jmcb/mjz077 |
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