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Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells

Gene regulation and metabolism are two fundamental processes that coordinate the self-renewal and differentiation of neural precursor cells (NPCs) in the developing mammalian brain. However, little is known about how metabolic signals instruct gene expression to control NPC homeostasis. Here, we sho...

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Detalles Bibliográficos
Autores principales: Rodrigues, Deivid Carvalho, Harvey, Emily M., Suraj, Rejitha, Erickson, Sarah L., Mohammad, Lamees, Ren, Mengli, Liu, Hongrui, He, Guiqiong, Kaplan, David R., Ellis, James, Yang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181744/
https://www.ncbi.nlm.nih.gov/pubmed/32332750
http://dx.doi.org/10.1038/s41467-020-15941-2